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Category: Articles

Econika Medical Engineering

Ameliorative effect of ozone on cytokine production in mice injected with human rheumatoid arthritis synovial fibroblast cells

Chang JD, Lu HS, Chang YF, Wang D. Department of Orthopaedics, Johnson General Hospital, 425 Chang Tsau Road, Changhua, Taiwan ROC. jonhsonchangmd@yahoo.com.tw?  Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by invasion of hyperplastic synovial cells and progressive joint destruction. Ozone therapy has been proposed as an immunomodulator and cellular metabolic activator which shows…
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Amelioration of ozone-induced lung injury by anti-tumor necrosis factor-alpha

Bhalla DK, Reinhart PG, Bai C, Gupta SK Department of Occupational and Environmental Health Sciences, College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48202, USA. ad6268@wayne.eduOzone Ozone(O(3)) is a significant component of atmospheric air pollution and produces detrimental effects in the lung. Although the mechanism of O(3)-induced lung inflammation and injury is…
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A primer of complementary and alternative medicine commonly used by cancer patients

Ernst E. School of Postgraduate Medicine and Health Sciences, University of Exeter, UK. E.Ernst@exeter.ac.ukComplementary and alternative medicine (CAM) is frequently used by cancer patients, and many oncologists have limited knowledge of CAM. This article provides a brief, evidence-based introduction to several CAM treatments relevant in the context of cancer. “Alternative” diets, chiropractic, coffee enemas, ozone…
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A comparative study between the clinical behavior and the RMI scan resolution in patients undergoing ozone therapy due to acute disk herniation with root compression

Ros J.M., Grangeat A., Prez A. and Croce E. (Argentina) The treatment of the acute herniation disk can be approached through various methods, some of them being non-surgical like discolisis with oxygen-ozone therapy (O2-O3). The aim of this paper is to analyse the progressive changes occurring in the RMI and the absence of correlation between…
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A comparativestudy of bactericidal activity of ozonized soluyions During treatment of inflammatory diseases of paradontium

S. Sorokina, M. Zaslavskaja.The Medical Academy of Nizhni Novgorod, RussiaThe problem of paradontium inflammatory diseases treatment is one of the most urgent problems in stomatology. In spite of an abundance of existing remedies and methods of treatment this problem is far from solution. It was noted periodontal pocket microflora accustomization to antibacterial preparations and allergic…
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Reaction of local immunity of a vaginal wound after application of the ozonized olive oil.

V.V.Mekhedko, E.I.Nazarov National Medical Academy of Postgraduate Education named after P.L.Shupyk, All-Ukrainian association of ozone therapists and manufacturers of the equipment. Research-and-production enterprise Econika, Ukraine, www.ozonetherapy.org Prolapsus of internal genitals gives up to 15 % among indications to surgical treatment of women in gynecologic hospitals of Ukraine. The tactic peculiarity in management of patients in…
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Condition of general immunity in response to application of the ozonized olive oil to a vaginal postoperative wound

V. V.Mekhedko, E.I.NazarovNational Medical Academy of Postgraduate Education named after P.L.Shupyk, All-Ukrainian association of ozone therapists and manufacturers of the equipment. Research-and-production enterprise Econika, Ukraine, www.ozonetherapy.org As it is known, ptosis and prolapsus of the internal genitals make up to 28 % in structure of gynecologic diseases. The basic method of treatment of this disease…
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Arteriovenous Difference in Blood Oxygen Saturation as a Diagnostic Index of Ozone Effect on the Organism

E.I.Nazarov Scientific-industrial venture Econika, Odessa, Ukraine Keywords: ozonetherapy, arteriovenous difference, blood oxygen. A bad distribution of methods of objective evaluation of physiological effect of ozone on the organism is one of the significant problems of ozone therapy. The given paper presents the preliminary data of using the method of express-measuring of venous blood saturation with…
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How much does ozone therapy need a real biochemical control system? The oxidative stress importance and assesment

Frank Hermandes Ozone Research Center, National Center for Scientific Research, POB.6880, Havana, Cuba. Ozone therapy is not officially allowed in many countries, but medical private services are using this therapy all around the world. However, appropriate control systems to assess the benefits and risks of systemic ozone therapy are not always used and in such…
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Controlled clinical trial on the use of ozonated blood as a treatment for retinitis pigmentosa

N. Moreno, O. Pel??ez, T. Alem??n, C. Barcel??. International Reference Center of Retinitis Pigmentosa “Camilo Cienfuegos”, Cuba. The aim of this study is to determine the effects of ozone as a therapy for patient with retinitis pigmentosa. A double blind, placebo controlled study was designed, in which 123 patients, ages 15 to 65 years, and…
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Ten year study in patients suffering from retinitis pigmentosa and treated with repeated cycles of ozone therapy.

M. Copello, S. Men?©ndez1, I. Horrach, J. Betancourt. National Reference Center of Retinitis Pigmentosa. Salvador Allende University Hospital, Cuba. 1Ozone Research Center, Cuba. Retinitis Pigmentosa is an hereditary disease of the retina which produces night blindness, peripheral visual field loss and narrowing of the central vision, which degenerates, after several years, in total blindness. This…
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Ozone inactivation kinetics of multiple antibiotic resistant strains of bacteria in water

GutiГ©rrez M.S., Lezcano I., Baluja Ch. and SГЎnchez E. Ozone Research Center, Cuba. ABSTRACT To determine the ozone inactivation kinetic of different Gram positive and Gram negative multiple antibiotics resistant bacterial strains from clinical isolation (CI), that resists too high concentration of chlorine, and compare them with reference strains was our objective. Microorganism’s concentration was…
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Changes in glutathione antioxidant pathway components, hla-dr and ige in blood from asthma patients treated with ozone therapy.

HernГЎndez F., Alvarez I., Corcho I. and GonzГЎlez M. Ozone Research Center, Cuba. ABSTRACT We have studied the behavior of the erythrocyte glutathione antioxidant pathway, the HLA-DR molecule expression and the serum IgE level in patients suffering reactive asthma, whose were treated with ozone major autohemotherapy or rectal insufflation. A subgroup of patients having high…
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Ozone therapy in patients with retinitis pigmentosa

Copello M.1, EguГ­a F.2, MenГ©ndez S.3 and MenГ©ndez N.1. 1Retinitis Pigmentosa National Reference Center, “Dr. Salvador Allende” Hospital, Cuba. 2″RamГіn Pando Ferrer” Ophthalmologic Hospital, Cuba. 3Ozone Research Center, Cuba. ABSTRACT Retinitis pigmentosa (RP) is characterized by progressive night blindness. The aim of this study is to determine the efficacy of ozone therapy in patients with…
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Ozone therapy effects in the oxidative stress associated to diabetes mellitus

Al-Dalien S.M.1, MenГ©ndez S.2, MartГ­nez G.1, FernГЎndez-MontequГ­n J.I.3, Candelario E.J.1 and LeГіn O.S.1. 1Center for Research and Biological Evaluation, University of Havana, Institute of Pharmacy and Food Sciences, Cuba. 2Ozone Research Center, Cuba. 3Institute of Angiology and Vascular Surgery, Cuba. ABSTRACT It is well recognized the presence of oxidative stress in diabetes mellitus. Ozone can…
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